Detection of methicillin-resistant Staphylococcus aureus strains resistant to multiple antibiotics and carrying the Panton-Valentine leukocidin genes in an Algiers hospital.
نویسندگان
چکیده
Forty-five Panton-Valentine leukocidin (PVL)-positive, methicillin-resistant Staphylococcus aureus strains were isolated in Algeria between 2003 and 2004; 18 isolates were isolated in the community and 27 in a hospital. Five PVL-positive hospital isolates were resistant to multiple antibiotics, including ofloxacin and gentamicin for three isolates.
منابع مشابه
شناسایی ژن‌های حدت پنتون والنتین لوکوسیدین (PVL) و مقاومت به متی‌سیلین (mecA ) در استافیلوکوکوس اورئوس جدا شده از نمونه‌های بالینی: یک گزارش کوتاه
Background and Objective: Staphylococcus aureus is a major pathogen of human in the world. Methicillin-resistant Staphylococcus aureus is associated with nosocomial infections. Recently, staphylococcal infections have been associated with the community. The purpose of this study was to isolate and identify Staphylococcus aureus virulence Panton-Valentine leukocidin (PVL) and methicillin...
متن کاملIsolation of PVL/ACME-Positive, Community Acquired, Methicillin-Resistant Staphylococcus aureus (USA300) from Iran
Introduction: Methicillin-Resistant Staphylococcus aureus (MRSA) is responsible for an increasing number of serious hospital- and community-acquired infections. USA300 is known to be the most common cause of community-acquired infections, but recently there have been some reports on hospital-acquired infections caused by this strain. Methods: Totally 171 isolates of S. aureus were collected fro...
متن کاملتعیین فراوانی ژن پنتون والنتین لوکوسیدین (PVL) و پروتئین‌های متصل شونده به کلاژن Cna در سویه‌های استافیلوکوکوس اورئوس جدا شده از نمونه‌های بالینی و بررسی مقاومت آنتی‌بیوتیکی: یک گزارش کوتاه
Background and Objective: Panton-Valentine leukocidin (PVL) toxin is a hemolytic exotoxin that increases the permeability of the cell membrane, thus causing lysis of leukocytes and tissue necrosis. Collagen-binding protein (Cna) adhesion Staphylococcus aureus is responsible for binding to collagen and the major virulence factor in arthritis and osteomyelitis. The purpose of this study was to in...
متن کاملPanton-Valentine leukocidin positive sequence type 80 methicillin-resistant Staphylococcus aureus carrying a staphylococcal cassette chromosome mec type IVc is dominant in neonates and children in an Algiers hospital.
Methicillin-resistant Staphylococcus aureus (MRSA) is a major antimicrobial drug-resistant pathogen causing serious infections. It was first detected in healthcare settings, but in recent years it has also become disseminated in the community. Children and young adults are most susceptible to infection by community-acquired (CA) MRSA strains. In this study 25 MRSA isolates implicated in infecti...
متن کاملDetection of Panton-valentine Leukocidin Gene Isoforms of Staphylococcus aureus Isolates in Al-Zahra Hospital, Isfahan-Iran
BACKGROUND Panton-Valentine leukocidin (PVL) is a gamma-toxin produced by Staphylococcus aureus encoded by genes lukS/lukF-PV with several single-nucleotide polymorphisms. A mutation at nucleotide position 527 results in substitution of histidine (H) to arginine (R) at amino acid 176. The groups defined based on the amino acid change, the "R isoform" group and the "H isoform" group. The purpose...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 50 3 شماره
صفحات -
تاریخ انتشار 2006